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Liquid dosage form - monophasic and diaphagic

Liquid dosage form



These are meant for both external and internal use. it is of 2 types

Monophasic liquid



monophasic liquid contains single layer or phase
These form the true solution because here the solute medicaments are mixed properly in the solution and form a homogeneous mixture

Example:-

External - Liniments , Lotions , Gargles , Throat paints , Mouth washes , sprays , Eye lotions , Eye drops , Nasal drop.

Internal - Syrups , Elixirs , Linctus and Drops
TRICK :- LET GNM
L two times and E two times for external and Dr. SELL for external

Internal ka Example dena hai toh pura sakal ki parts mein use hone wali chize yaad rakho just like teeth , nasal drops , eye drops , mouth washes




Complexation

1) liniments = an embrocation for rubbing on the body to relieve pain, especially one made with oil.

2) Gargles = liquid that wash one's mouth and throat with a liquid that is kept in motion by breathing through it with a gurgling sound.

3) Throat paints = Throat paintsare the viscous liquid preparations used for the mouth and throat infections. Glycerin is commonly used as a base because being viscous it adhere to mucous membrane for a long period and it possesses a sweet taste.

4) Elixirs (external) - a sweetened, aromatic solution of alcohol and water containing, or used as a vehicle for, medicinal substances.

5) Linctus (external) - thick liquid medicine, especially used for cough treatments.



2. BiPhasic



These are the liquid dosage form which have two phases one is solid and another one is liquid are called as biphagic liquid. These two phages can only be mixed with the help of immunifing (or) suspending agents.

TRICK :- Isme 2 phase hota hai solid and liquid jisko milane k liye shake karna padta hai. agar liquid dono 2 layer form karte hain toh unko milane k liye immunifing agent use hota hai.



Complexation

1) Suspending agent = a substance (such ascarrageenan,xanthan gum, orcellulose ether) that is added to fluids to promote particle suspension or dispersion and reduce sedimentation

2) Immunifing agent= It lower down the surface tension between two phasic layers and allow particles to mix completely


Oil water relation

1) o/w - oil in water (oil is in dispersed phase and water is the dispersion medium)

2) w/o - water in oil (water is in dispersed phase and oil is in dispersion medium)



All notes is posted by ABC.Ek
(student of Hitech college of pharmacy)

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